Biologique Recherche 

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Biologique Recherche is a French skincare line known for remarkable effectiveness based on a clinical but individualised approach to skin care.  Biologique Recherche has over 40 years of experience and a unique philosophy in high-end personalised skin care, with pure, concentrated, raw ingredients used to develop the most powerful and effective skin care products combined with innovative protocols and procedures.


No artificial fragrances are used in order to preserve the integrity of formulas and to avoid unnecessary adverse reactions. All products are safe to use during pregnancy and breastfeeding.

Visit our online skincare shop here

The Biologique Recherche methodology uses three fundamental stages:

The Assessment Stage

The Skin Instant Lab is a scientific-grade skin analysis machine with probes to measure hydration levels, trans-epidermal water loss, elasticity, pigmentation and sebum production levels. This is recorded using a specialised diagnostic analysis to allow the prescription of a highly individualised skin care regimen and to monitor changes in the skin over time, providing dynamic assistance to modify skin care regimens over time.

The Initialisation Stage

The Initialisation Stage is a crucial part of the Biologique Recherche Methodology. During this stage, the epidermis is thoroughly cleansed, its pH is balanced, it is gently exfoliated and its proteo-lipidic film is restored. Impurities and dead cells are gradually brought to the surface and eliminated. After gentle exfoliation and mask treatment, the skin is ready to receive Treatment Stage products.

The Treatment Stage

During the Treatment Stage, products containing the highest concentrations of active ingredients are applied to "recondition" the epidermis and help activate both its regeneration properties and those of the skin's deeper structures. Products used during this phase balance, hydrate and revitalize the epidermis to progessively improve the quality of the skin and leave the complexion radiant.

Cleansing Lotions


Lait VIP 02

The Lait VIP O2 is the ultimate cleanser for the city dweller, or anyone exposed to pollution. This oxygenating cleansing milk gently removes makeup and impurities, whilst protecting the skin against external elements, such as harsh climates and pollution. The secret BR Oxygenating Complex contains perfluorodecalin, a compound known to enhance oxygen delivery, stimulating cell exchange and improving skin health. More than just a cleanser, this milk will rebalance and re-oxygenate the skin. 

Recommended for: Stressed, devitalised skin


The P50 range: Balancing Exfoliating Lotions


The P50 Range of Lotions are the cult products of Biologique Recherche. All Biologique Recherche skin care regimens, whether administered at home or in a beauty institute, begin with the “P50 Ritual”, due to their proven efficacy and results. These famous and coveted P50 Lotions are specially formulated to gently exfoliate the skin, regulate excessive sebum secretion, purify, moisturise, regenerate and help maintain the epidermis’ acid pH.

These balancing and exfoliating lotions speed up the epidermis’ natural exfoliating process and the reconstruction of the epidermal shield. The fortified epidermis can then fulfil its protective functions completely, enhancing the skin’s self-regeneration potential. The chemical exfoliation of the skin results from a carefully combined cocktail of hydroxy acids. As its name indicates, the Lotions P50 gently renews the skin over 50 days – ‘P’ stands for peeling and ‘50’ stands for 50 days – which represents about two epidermal cycles, for a gentle yet effective exfoliating process.They are applied in the morning and in the evening. These lotions also allow increased penetration and enhanced action of products applied after their use.

Vogue described P50 as ‘a miracle in a bottle’ while called the tonics ‘life changing....’ 


 There are four different versions of Biologique Recherche’s P50 Lotions: Lotion P50, Lotion P50V, Lotion P50W and Lotion P50 PIGM400. Each one provides the same core benefits, but their formulations change slightly to suit each and every skin type.


Lotion P50W

The Lotion P50W has a gentler approach out of all our Lotions P50. Not only it penetrates the epidermis quite slowly, it was also specifically formulated with arnica for its anti-inflammatory and healing properties to provide a soothing effect on the skin.

Recommendation: This mild version is suitable for thinner, reactive and normal skin types or patients with rosacea


Lotion P50V

The Lotion P50V is a version of P50 that was specifically formulated with added vitamins and walnut extracts, to inhibit the ageing process and nourish the epidermis. The antioxidant ingredients of this lotion make it suitable for more mature and/or devitalised Skins Instants®.

Recommendation: Devitalised and/or pigmented and/or less toned skin types


Lotion P50 PIGM400

The Lotion P50 PIGM400 is the latest formulation and is enriched with both the exfoliating active ingredients of the Lotion P50 and the brightening agents and antioxidants of the PIGM400 range. Thanks to a combination of flavonoids and wasabi extracts, this version of the Lotion P50 helps to regulate melanin synthesis while respecting and protecting the skin. This is a complete solution that helps to recover a luminous and radiant skin with an even and lightened complexion.

Recommendation: Ideal for skin types with dull complexions and or hyperpigmentation


All Biologique Recherche masks have been carefully developed to meet the needs of a spectrum of ski types. They contain high concentrations of active ingredients to balance the epidermis, such as essential fatty acids to replenish after exfoliation and prepare the skin for the products that are applied during the treatment stage. At Biologique Recherche the masks are applied in the middle of the skin care programme to avoid removing the active ingredients used in the treatment stage along with the mask.


Masque VIP 02

Masque VIP O2 is a refreshing and oxygenating anti-pollution mask. Containing marine elastin to moisturise, white clay to purify, BR oxygenating complex to brighten, essential fatty acids of omega 3 & 6 to moisturise and cucumber extract to calm and soothe, this is a mask we recommend for all skin types to use at home to regenerate, revitalise and tone the skin and to remove dark circles from under the eye area.

Recommendation: Stressed, dull and devitalised skin types.

Masque Visolastine E

Masque Visolastine E brightens and refreshes the complexion, helps to reduce the signs of ageing and provides hydration and comfort to the skin. This non-drying mask contains purifying agents of white clay, essential fatty acids of omega 3 & 6 to recondition the skin, marine elastin and cellular oligopeptide of amniotic fluid to regenerate and moisturise the epidermis. This is an extremely moisturising and re-lipidating mask

Recommendation: All skin types, particularly dry, devitalised and/or mature skin types

Intensive Creams

The Intensive Creams are the most complex and sophisticated creams of the Biologique Recherche range. They are formulated for skin types that require more intensive treatment, with tailored benefits.


Crème Masque Vernix

Hailed as a ‘true marriage of science and beauty’, Crème Masque Vernix virtually reproduces the original composition of the newborn’s vernix – the first epidermal protective barrier at birth – thanks to a selection of active ingredients rich in lipids, proteins and antioxidant peptides. Vernix, a sebaceous waxy substance, has powerful healing properties, balances the pH of the skin and inhibits the growth of bacteria for a multi-pronged approach to skin replenishment. This 2-in-1 product helps recondition and strengthen deficient and/or stressed epidermis by offering it a “second birth”; it can either be used as a mask or a cream, for those in need of an intensive treatment. Thanks to its hydrating, repairing and protecting actions, Crème Masque Vernix reduces transepidermal water loss, repairs the DNA of skin cells damaged by UV rays and minimises the effects of ageing.

Recommendation: Devitalised or stressed skin types


Crème VIP O2

The Crème VIP O2 is the perfect anti-pollution, anti-ageing, oxygenating cream to produce revitalised and healthy skin. This cream contains a combination of active ingredients to hydrate and oxygenate the epidermis. The revolutionary Specific BR Oxygenating Complex helps to brighten, the Cellular oligopeptide of Mink regenerates and the Hyaluronic Acid moisturises.

Recommendation: Tired and/or devitalised skin types, particular city workers and smokers


La Grande Crème

La Grande Crème is la crème de la crème! Biologique Recherche’s newest innovation is the fruit of years of research and development. To develop this pioneering formulation, Biologique Recherche identified and selected EpigenActiv’©, a peptide that acts on Epidermal Growth Factor (EGF) receptors, essential to regenerate tissues and recycle degraded proteins. With a number of carefully selected active ingredients, La Grande Crème does not just reverse DNA damage and rejuvenate cells but also prevents cutaneous ageing, diminishes pigmentation irregularities and reinforces the skin barrier. Beautifully presented in a custom-made artisanal yet revolutionary glass packaging with gold features to evoke both the excellence and the scientific innovation of La Grande Crème.

Recommendation: Ageing skin  


Crème Contour Yeux et Lèvres Biofixine

The Crème Contour Yeux et Lèvres Biofixine conceals wrinkles, prevents their appearance and limits further weakening of the skin while respecting the natural appearance of the face. Adapted for all skin types, it deeply moisturises the fragile skin of the eye and lip contour. Indeed, the lack of collagen, elastin and adipose cells coupled with the repeated contractions of these facial compartments make both the eye and lip contours prone to dryness, sensitivity and ageing. Thanks to its numerous anti-ageing active ingredients, this 2-in-1 cream immediately smooths and lifts the skin whilst plumping out wrinkles. This treatment is specifically formulated for the eye and lip contour to reveal the beauty of the eyes and reshape the lips.

Recommendation: All skin types, particularly for marked by the signs of ageing

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